Sunday, 20 March 2016

Obesity off-switch: An enzyme in the brain controls overeating

Obesity off-switch: An enzyme in the brain controls overeating

A paper published in the latest edition of the journal Science has revealed a key enzyme that acts as a control for overeating and obesity. Though the enzyme O-GlcNAc transferase (OGT) was known to be involved in both neuronal development and insulin signalling, the enzyme’s precise role in the mature brain was largely unknown.

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