Apart from the wide-eyed bike ride home from the lab, his neighbour turning into a witch, the threatening behaviour of his furniture and the futile battle to save his ego from collapse, Dr Albert Hofmann appeared to enjoy his first trip on LSD. Now, 75 years after the Swiss chemist witnessed the full effects of his psychedelic invention, scientists have discovered fresh details of how the drug affects the brain. Scans of healthy volunteers show that less than half the dose that left Hofmann cowering on his sofa makes a person’s sense of self disintegrate.
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