New research suggests that those with bipolar I and a history of migraines should avoid taking lithium

A new study in Brain and Behavior has unraveled the relationship between migraines, bipolar disorder, and patient outcomes. Nicole Sekula and colleagues conducted an 11-year longitudinal study demonstrating that those with bipolar disorder and migraines experienced worse symptoms of depression, mania, and a diminished quality of life on average. In addition, if those individuals were also prescribed lithium, their symptoms of mania were worse than those with migraines not taking lithium.

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