New drugs that unleash the immune system on cancers may backfire, fueling tumor growth
Although the 65-year-old woman had a rare type of endometrial cancer that had spread to her liver and was expected to be fatal, she still felt well enough to work and swim. As a last hope, her doctors gave her a type of immune-stimulating drug that had had near-miraculous results in some patients with advanced cancer. But 3 weeks after she began the drug, the woman's liver tumors had grown, and her abdomen was swollen with tumors as big as oranges.
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